Hiba M. Saleem; thaer A. SALIH
Abstract
The present study was aimed to investigate one of the causes for unexplained recurrent spontaneous abortion at first trimester of pregnancy by determining the levels of Oxidative stress ...
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The present study was aimed to investigate one of the causes for unexplained recurrent spontaneous abortion at first trimester of pregnancy by determining the levels of Oxidative stress (Malondialdehyde) and determine the levels of Antioxidant defense system(Superoxide dismutase, Trolox equivalent antioxidant capacity, Total Antioxidant Capacity)on pregnant women with unexplained recurrent spontaneous abortion at first trimester of pregnancy compared with control group, as well as study the relationship between maternal age and the incidence of recurrent spontaneous abortion .This study has been accomplished using 60 of blood samples of women in Baghdad and have been divided into 50 pregnant women with unexplained recurrent spontaneous abortion at first trimester of pregnancy (patients) and 10 pregnant women at first trimester of pregnancy without any history of recurrent abortion (control).The results of statistical analysis of the present study showed: There was a significant increase in percentage and number of incidence of abortion with Aging of pregnant women who had unexplained recurrent spontaneous abortion at first trimester of pregnancy compared with control group and the highest percentage was found in women age greater than 35 years (47.368%) of more than four cases of occurrences Unexplained Recurrent Abortion at first trimester of pregnancy .There was a significant increase (P≥0.05) in level of MDA in pregnant women with unexplained recurrent abortion at first trimester of pregnancy compared with control group, and there was a significant decrease(p ≤ 0.05) in level of Antioxidant SOD , TEAC , TAC in patients compared with control group .
