ASMAA JUMAA ALSAMMARAI
Abstract
The present study concerned the effect of Aluminum Sulfate on some of liver and the kidney enzymes in white rat '' Rattus norvegicus '' . had used twelve rats for adult male and divided ...
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The present study concerned the effect of Aluminum Sulfate on some of liver and the kidney enzymes in white rat '' Rattus norvegicus '' . had used twelve rats for adult male and divided to four groups the concentration of Aluminum sulfate in first group was 75 mg 100 ml of distilled water the second was 150 mg 100 ml of distilled water & third 300 mg 100 ml of distilled water that’s gave as 1 ml per day ; the first group is considered as control group , while the other three groups are experimental groups . The study have found there are significant differences in ALP, ALT and AST enzymes in addition to Creatinine and Urea with dosage increase concentration of Aluminum sulfate by compare with control group (P≤0.05) However , there are no significant differences in ALT enzyme when concentration of this dosage is increased among experimental groups ( 1,2,3 ) . Adding to that there are significant differences in AST enzyme when concentration of this dosage is increased in experimental groups 1 , 2 and 3 (P≤0.05) while there are no significant differences in ALP and Urea when the concentration of the dosage is increased in comparison with experimental group 1,2,3 (P≤0.05).Finally , they are significant differences in Creatinin when the concentration of the dosage is increased in the experimental groups in comparison with 1,2 and 3 (P≤0.05 .The study shows that Aluminium sulfate effect negatively on the level and the activity of liver ALP ,ALT , and AST enzymes , Also , It has negative effect in the activity and the level of both creatinine and urea of kidneys whatever the concentration of the dosage in the water it was . In addition to that , there are differences in the effect of Aluminium sulfate on the ALP ,ALT , AST enzymes and creatinin and urea concerning levels of their activities inside Ruttus
