Synthesis of Several New Schiff Bases Linked to Sulfonamido Naphthalimide Moiety with Expected Biological Activity.

Marouf Al-Azzawi, Ahlam; Solaiman Hamed, Ahmed

doi:10.37652/juaps.2014.123915

Document Type : Research Paper

Authors

¹ University of Baghdad - College of Science

² University of Anbar- College of Veterinary Medicine

https://doi.org/10.37652/juaps.2014.123915

Abstract

Several new Schiff bases linked to sulfonamidonaphthalimide moiety have been synthesized. The first step in this work involved introducing of 4-(N-naphthalimidyl) phenyl sulfonylchloride in amination reaction with hydrazine hydrate producing 4-(N-naphthalimidyl) phenyl sulfonylhydrazine. Introducing of the prepared sulfonyl hydrazine in condensation reaction with different substituted aromatic aldehydes in the second step afforded the target new Schiff bases. Structures of the prepared compounds were elucidated on the basis of FTIR, 1HNMR, 13CNMR spectral data which agreed with the proposed structures. The newly synthesized compounds are expected to have biological activity scince they are built from biologically active components including naphthalimide, sulfonylimide and Schiff base.

Keywords

Main Subjects

Chemistry

References

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Journal of University of Anbar for Pure Science

Synthesis of Several New Schiff Bases Linked to Sulfonamido Naphthalimide Moiety with Expected Biological Activity.

References

References

Volume 8, Issue 2
August 2014
Page 47-52

Synthesis of Several New Schiff Bases Linked to Sulfonamido Naphthalimide Moiety with Expected Biological Activity.

References

References

Volume 8, Issue 2August 2014Page 47-52

Volume 8, Issue 2
August 2014
Page 47-52