The relationship between homocysteine , folate, B12 serum level and breast cancer in sample of women in Baghdad city –Iraq.

D. Salman, Ehab; A. Al Bayyar, Ezeddin; K. Ibrahim, Reem

doi:10.37652/juaps.2016.132435

Document Type : Research Paper

Authors

¹ University of Baghdad- College of Science

² University of Al -Anbar - College of Science

³ University of Anbar - College of Science

https://doi.org/10.37652/juaps.2016.132435

Abstract

The study included eighty cases of women with breast cancer (as patients group) with age range from 30 to 8years, The control group included twenty healthy women. The level of Homocysteine, vitamin B12 and folate were estimated in the serum of patients group and compared with the control and it has been compared to some other aspects such as aBody mass index (BMI), type of feeding and Family history. The statistical analysis revealed a significant difference (p ≤ 0.05) between the mean of Homocysteine level (13.18 ± 0.61) µmol/l for patients group compared with mean (9.78 ± 0.60) µmol/l of control group . It was also found a significant difference (p≤ 0.05) between the mean of folate level for patients group and control group , (8.64 ± 0.40) ng/ml and (13.19 ± 1.19) ng/ml for both groups, respectively,.It was noticed that there was interaction between the mean of homocysteine, B12 and folate level in serum with age, marital status ,type of feeding and family history.

Keywords

Main Subjects

Biology

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Journal of University of Anbar for Pure Science

The relationship between homocysteine , folate, B12 serum level and breast cancer in sample of women in Baghdad city –Iraq.

References

References

17-Xinran, X. and Jia, C. 2009. One-carbon metabolism and breast cancer: An epidemiological perspective.J Genet Genomics , 36: 203–214.

18-Lewis, S.J.; Harbord, R.M.; Harris, R.; Smith, G.D. 2006 . Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk. J. Natl. Cancer Inst,98:1607–1622.

Volume 10, Issue 1
April 2016
Page 1-6

The relationship between homocysteine , folate, B12 serum level and breast cancer in sample of women in Baghdad city –Iraq.

References

References

17-Xinran, X. and Jia, C. 2009. One-carbon metabolism and breast cancer: An epidemiological perspective.J Genet Genomics , 36: 203–214.

18-Lewis, S.J.; Harbord, R.M.; Harris, R.; Smith, G.D. 2006 . Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk. J. Natl. Cancer Inst,98:1607–1622.

Volume 10, Issue 1April 2016Page 1-6

Volume 10, Issue 1
April 2016
Page 1-6