A study of some blood changes for patients with urticaria

H. Farhan, Hamed; O. Al-mawla, Saleem; Q. Al-ani, Mohammed

doi:10.37652/juaps.2017.145235

Document Type : Research Paper

Authors

College of Science, University of Anbar

https://doi.org/10.37652/juaps.2017.145235

Abstract

The present study aims to determine changes in some blood components in patients with urticaria, included measurement of Complete Blood Count CBC, estimate thyroid hormone levels of thyroid T3 and T4 and TSH , in addition to estimating levels of antithyroglobulin Anti-Tg in the serum of patients with urticaria reviewers health centers in the town of Khalidiya and outpatient clinics in the town of Khalidiya-Anbar and Amiriyah-Baghdad for the period from 15/1/2016 up to 15/05/2016.
The results showed no significant differences for each of the red blood count RBCs and Hb concentration and platelet count PLT at the level of probability (P <0.05). The results also show a simple occurrence of a significant increase in the number of white blood cells WBCs when (P <0.05). A slight significant decrease in the proportion of compressed blood cells P.C.V when (P <0.05). Occurrence of significant increase in the deposition of the red blood cells at the rate of ESR (P <0.05). Occurrence of simple significant increase in Thyroid Stimulating Hormone (TSH) rates at (P <0.05). Occurrence of a significant increase in a simple Triiodothyronin (T3) rates at (P <0.05). Occurrence of simple significant increase in Thyroxin hormone (T4) rates at (P <0.05). Occurrence of significant increase in the rates of antithyroglobulin Anti-Tg at (P <0.05). We conclude from the results of this study, a correlation between urticaria disease and thyroid disorders, and that the rise in the number of rates of white blood cells in patients emphasizes the role of hypersensitivity reactions in patients with urticaria, and high Erythrocyte sedimentation rate ESR may indicate interactions inflammatory associated with disease

Main Subjects

Biology

References

(1) Raksha, M., Roshni, A., Kiran, K., et al., (2014). A Clinical Study OF Urticaria And Angiodema With Particular Reference To The Etilogy. NJMDR. 4(2) :132-137.

(2) Zitelli , KB., Cordoro , KM., (2011). Evidence based evaluation and management of chronic urticaria in children. Pediatric Dermatology. 28, 629-639.

(3) Kataria, U., Chhillar, D., (2015). An etiopathological study of urticaria in a tertiary care center in Northern India. IAIM. 2(9): 61-64.

(4) Laliv , K., Shmuel , K., (2013).Urticaria and Angioedema in Pregnancy. Curr Dermatol Rep. 2:236–242.

(5) Kanani, A., Schellenberg, R., Warrington, R., (2011). Urticaria and angioedema. Allergy Asthma Clin Immunol. 7 (1):S9.

(6) Greaves, MW., Tan, KT., (2007). Chronic urticaria: recent advances. Clin Rev Allergy Immunol. 134-43.

(7) Sheikh, J., (2005). Autoantibodies to the high-affinity IgE receptor in chronic urticaria: how important are they? Curr Opin Allergy Clin Immunol. 5: 403-7.

(8) Poonawalla, T., Kelly, B., (2009). Urticaria: A review. Am J Clin Dermatol. 10:9–21.

(9) Kozel, MM., Mekkes, JR., Bossuyt, PM., Bos, JD., (2001). Natural course of physical and chronic urticaria and angioedema in 220 patients. J Am Acad Dermatol. 45(3):387–91.

(10) Kaplan , AP., (2004). Chronic urticaria Pathogenesis and treatment. Allergy Clin Immunol. 114 : 265-74.

(11) Brzoza, Z., Kasperska-Zajac, A., BaduraBrzoza, K., et al., (2008). Decline in dehydroepiandrosterone sulfate observed in chronic urticaria is associated with psychological distress.Psychosom Med.70:723–8.

(12) Amar, SM., Dreskin , SC., (2008). Urticaria. Prim Care. 35(1):141–57.

(13) Zauli,D.,Grassi, A.,Ballardini, G., et al.,(2002).Thyroid autoimmunity in chronic idiopathic urticaria. Am J Clin Dermatol. 3: 525-8.

(14) O’Donnell, BF., Francis, DM., Swana, GT., et al., (2005). Thyroid autoimmunity in chronic urticaria. Br J Dermatol. 153: 331-5

(15) Fusari, A., Colangelo, C., Bonifazi, F., et al., (2005). The autologous serum skin test in the follow-up of patients with chronic urticaria. Allergy. 60: 256-8.

(16) Greaves , MW., (2003). Chronic idiopathic urticaria. Curr Opin Allergy Clin Immunol.3: 363-8.

(17) Benjamini , E., CoCo , R., Sunshine,G., (2000). Immunology. A sort Course. 4th(Ed). Wiley-Liss. Canada.

(18) Sherwood , L., (1991). Fundamentals of physiology:A human perspective. Whest Publishine company. U.S.A.

(19) Chen, JF., Chung, MH., Liu, YC., Wang, WM.,(2012). A Study of Patients with Chronic Idiopathic Urticaria. J Med Sci.32(5):233-8.

(20) Tajima, K., Sato, S., Kato, T., (2016). Prolonged Pancytopenia in Chronic Urticaria Following Treatment with Cetirizine. Austin J Clin Case Rep. 3(1): 1085.

(21) Powell, RJ., Du Toit, GL., Siddique, N., (2007). BSACI guidelines for the management of chronic urticaria and angio-oedema. Clin Exp Allergy. 37(5):631-50.

(22) Sood, R., ( 2006 ) , Textbook of Medical Laboratory Technology , 1st Edition , Jaypee Brothers , India.

(23) Dave, JM., Taylor, P., Grange, JM., Gaya, H., (1986). A new enzyme-linked fluorescence assay (ELFA) for use with peroxidase-anti body conjugates: a comparison with ELISA for the quantitation of IgM antibodies to hepatitis B core antigen. J Med Micro .21: 271-4.

(24) Naeem, R., Muhammad, S., Shoaib, A., Nasser, R., Liaquat, A., (2008). A Clinical Study of Papular Urticaria , J. Coll. Physicians Surg Pak. 18(3): 147-150.

(25) Ferrer, M., (2015). Immunological events in chronic spontaneous urticaria. Clin Transl Allergy.5: 30.

(26) Kasperska-Zajac, A., Brzoza, Z., Rogala, B., (2008). Increased concentration of platelet-derived chemokines in serum of patients with delayed pressure urticaria. Eur Cytokine Netw. 19(2):89-91.

(27) reaves, M., (2000). Chronic urticaria J Allergy Clin Immunol. 105: 664-72.

(28) Levy, Y., Segal, N., Weintrob, N., Danon , Y L., (2003). Chronic urticaria: association with thyroid autoimmunity. Arch Dis Child. 88:517–519.

(29) Iram, S., Shoaib, T., Farrukh, M., Alina, A., (2010). Frequency of Autoimmune Thyroid Disease in Chronic Urticaria. J. Coll. Physicians Surg Pak. 20 (3): 158-161

(30) Saunier, B., Tournier, C., Jacquemin, C., Pierre, M., (1995). Stimulation of mitogenactivated protein kinase by thyrotropin in primary cultured human thyroid follicles.J Biol Chem.270:3693–97.

(31) Bansal, AS., Hayman, GR., (2009). Graves disease associated with chronic idiopathic urticaria: 2 case reports. The J Investig Allergol Clin Immunol. 19(1):54-6.

(32) Iram , S., Usama, Kh., Nighat, M., (2016). Association Between Chronic Idiopathic Urticaria And Body Mass. Index. Pakistan Journal of Physiology . 12 (1):35-37.

(33) Aversano , M., Caiazzo, P., Iorio, G., et al., (2005). Improvement of chronic idiopathic urticaria with l-thyroxine: a new TSH role in immune response?. Allergy : 60: 489–493.

(34) Kumar, A., Kuril, S., Kilaikode, S., Saenger, P., (2013). Chronic urticaria and angioedema associated with Hashimoto’s thyroiditis in a child: A case report. IJCRI s. 4(11):635–637.

(35) Aamir, I.S., Tauheed, S., Majeed, F., Atif, A., (2008). Serum anti-thyroid antibodies in female patients with chronic urticaria. J. Coll. Physicians Surg Pak.18 (8): 498–501.

(36) Najib, U., Sheikh, J., (2008). The spectrum of chronic urticaria. Allergy Asthma Proc. 30: 1-10.

(37) Nuzzo,V., Tauchmanova, L., Colasanti , P., et al., (2011).Idiopathic chronic urticaria and thyroid autoimmunity Experience of a single center. Dermato-Endocrinology. 3:4, 255-258.

(38) Yadov, S., Upadhyay, A., Bajoj , A.K., (2006). Chronic Urticaria : An overview. Indian J Edrmatol.51:171-7.

(39) Erge, D., Catal, F., Topal, E., et al., (2015). Determination of Acute and Chronic Urticaria Based on C-Reactive Protein or Mean Platelet Volume Levels. IJAR. 5 (4) : 506-508.

(40) Caminiti, L., Passalacqua, G., Magazzù, G., et al., (2005). Chronic urticaria and associated coeliac disease in children: a case-control study. Pediatr Allergy Im. 16(5):428-32.

(41) Cheng-Han,Wu., Efrem,E., Michael, R., Carina, V. , (2015). Association between Micronutrient Levels and Chronic Spontaneous Urticaria. Biomed Res Int.926167.

(42) Lai, K., Su, C., (2010). Association of Chronic Urticaria with Rheumatic Diseases and Thyroid Autoimmunity. Journal of Internal Medicine. 21：277-284.

Journal of University of Anbar for Pure Science

A study of some blood changes for patients with urticaria

References

References

Volume 11, Issue 3
December 2017
Page 43-50

A study of some blood changes for patients with urticaria

References

References

Volume 11, Issue 3December 2017Page 43-50

Volume 11, Issue 3
December 2017
Page 43-50