Document Type : Research Paper

Author

Medical Technical Institute - Mansour

10.37652/juaps.2011.15410

Abstract

استخدمت فی الدراسة 112 فاراً أبیض سوسریاً لدراسة تأثیر کلورید الکوبلت على نسیج الخصیة، قسمت الى مجموعات اساسیة وثانویة وفقاً للتراکیز والجرع المستخدمة، وحضرت منها شرائح نسیجیة وتم صبغها بالصبغة الروتینیة (الهیماتوکسلین - ایوسین) لغرض فحصها ودراستها مجهریاً ، واظهرت مقاطع الخصى تغیرات نسیجیة مرضیة واضحة وازدادت بزیادة التراکیز والجرع المستعملة. حیث لوحظ انتشار السائل الوذمی (Oedemo) وحدوث نزف دموی (Haemorrhage) واحتقان الاوعیة الدمویة وکذلک انفصال الظهارة المنویة (Seminiferous epithelium) وتبعثر النسیج البینی (Interstitum) وضمور خلایا لیدک (Leydig cells) ووجود الخلایا العملاقة متعددة النوى Giant cells) (Multinuclitated والحطام النخری (Nectrotic debris)، مما یدل على حدوث تأثیرات سامة وتنخر (Necrosis) حاد للانسجة وموت الخلایا المسؤلة عن نشأة النطف (خلایا سرتولی) واسلاف النطف والخلایا النطفیة الاولیة والثانویة وطلائع النطف فی نسیج الخصى (Sertole. Cells Spermatogonia, pri & Sec spermatocytes, Spermatede).

Main Subjects

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