Document Type : Research Paper
Authors
University of Al-Anbar- Coll. of Education for Pure Science
Abstract
This study was done in Fallujah Hospital and AL-Jameaa medical Lab in Fallujah city since the beginning of February of 2009 until June 2009. Hormonal changes in the serum of polycystic ovary syndrome (PCOS) infertile women in Fallujah city and there countryside’s were studied. Forty infertile women affected with increase of testosterone were selected, twenty of them with (PCOS) compared with twenty normal women. All of the women in this study from Fallujah city and surrounded area with different ages. All women showed the same symptoms, like hair growth in face, bold voice with an increase in testosterone and increase in LH while there no differences in FSH level. The levels of Prolactin was increased at (12.5%) .In conclusion the high levels of testosterone is responsible of hirsutism studeid in women lead to presence of the secondary characters of men in women and this because of high levels of in free androgens which lead to the increase estrogen in esteron form that make a appositive feed back on LH secretion which lead to increase testosterone secretion from the ovary.
Keywords
Main Subjects
- Harris C. and Carey A. A 2000. Women Guid to Dealing with Pcos,Thorsons . The McGraw-Hill Companies, Inc. new York 86-96.
- Buchholz MH, Carey DG, Norma RJ. Restoration of Reproductive potential by lifsty modification in obese polycystic ovary syndrome: Role of insulin sensitivety and Luteinizing hormone. J Clin Endocrinal Metab, 1999; 84 (4): 1470 – 1474.
- Griffing GT. Hirsutism. e Medical J, 2002; 3 (11): 1-19.
- Waheed N. K. Ovarian polycystic disease. e Medicine J, 2003; 3(9): 3-13.
- European Society for Human Reproduction and Embryology / American Society of Reproductive Medicine ESHRE/ASRM- sponsored PCOS consensus workshop group (Rotterdam). Revised 2003 consensus on criteria and long term health risks related to polycystic ovary syndrome (POCS) .Human reproduction J,2003(1)19-45
- Frank S. Polycystic ovary: a changing perspective. Clin Endocrinal, 1989; 31 (1): 100 – 120.
- Jubiz W. Endocrinology A logical Approach for Clinicians, 2nd edition, McGraw-Hill Book Company, New York, 1985; 227 – 231.
- Arslanian SA, Lewy Vd and Danadian K. Glucose Intolerance in obese Adolescents with polycystic ovary syndrome: roles of insulin Resistance
- World Health Organization (WHO) 1984. Work shop on the standardized investigation of the infertile couples. Moderator p Rowe coordinator M. Darling. In: proceeding of the 11th world congress on fertility and sterility. Harris RF(eds). MTP press Ltd, Lanccaster, Boston, The Hage Dordrecht, pp.27-431.
10. Speroff L, Glass RH, Kase NC. Clinical Gynecology Endocrinology and infertility, 6th edition, Lippincott Williams and Wilkasn, Philadelphia, 1999; 37 – 90, 522 – 543.
11. Hershag A, Peterson CM. Endocrine disorders. In: Novak's Gynecology, Berek Js, Adashi EY, Hillard PA, 12th edition, 1996; 916,833,854,795,797.
12. Gill Gn, Kokka, Jp, Mandell Gl. Cecil Textbook of Medicine, 20th edition, Vol. 2 , saunder Company, Philadelphia, 1996; 1086 – 1168.
13. Hopkinson Z.E.C., Zattar N., Fleming R. and Greer R.A. (1998)Polycystic Ovarian Syndrome: the metabolic syndrome comes to gynaecology, British Medical Journal 1998;317: (2) 329-30, (3) 330, (4) 329, (8) 331, (9) 331, (12) 331
14. Ehrmann D.A. ,Poly cystic ovary syndrome ,The New England Journal of Medicine 2005(12)329-352
15. Franks S, Polycystic ovary syndrome. New England journal of Medicine, 1995;21:854-857
16. American Society for Reproductive Medicine ASRM (2003) Hirsutism and polycystic ovarian syndrome :A Guide for patient ,patient information series 2003:11-12
17. Schlethte , J.A. Prolactinoma.New England Journal of medicine . 2003;349 (21):2035-2036
18. Goldfien A. and Moriroe SE. Ovaries. In: Basic and clinical endocrinology, greenspon Fs, Forshman PH, Lange medical publication, California, 2001; 453–507.
19. Lobo RA, Carmina E.The important of diagnosing the polycystic ovary syndrone. Ann Intern Med, 2000; 132 (12): 989 – 993.
20. Kiddy DS , Fairly DH. and Seppala M, Diet –induced changes in sex hormone binding globulin and free Testosterone in women with normal or polycystic ovaries :correlation with serum insulin and insulin like growth factors -1 Clin Endocrinology ,1989;31:797-763
21. Frank S. Polycystic ovary: a changing perspective. Clin Endocrinal, 1989; 31 (1): 100 – 120.
22. Morales A, Laughin GA, Butzow Tumors,et al .Insulin somatotropic , and lutinizing hormone axes in laen and obese women with polycystic ovary syndrome :common and distinct feature . J clin Enocrinol Meta, 1996; 81:2854- 2864.
23. Beaker KL. Principle and practices of endocrinology and metabolism, 3th edition, Lippincott Williams and Wilkins, Philadelphia, 2001; 918-1015
24. Braunwald E, Issel basher KJ, Robert GP- Harrison's principle of Internal Medicine Mcgraw Hill Company, New York, Sanfrancisco, 2002; 2097 – 2120, 292, 294, 2263 – 22650
25. Guzick D. Polycystic ovary syndrome: Symptomatology, pathophhsiology, and epidemiology. Am J Obstet Gynecol, 1998; 179 (6): 89 -93.
26. Goldzieher JW .polycystic ovarian diseases. Fertil Steril, 1981; 35:371-394.
27. Konerman M, Peine S, Rehling H, et al. PCO syndrome and sleep –related Breathing Disorders. Sleep Res, 2003; (151): 7 – 11.
28. Darweish,A. Al Merai M. and Dway R. Hirsutism: Casual Study Tishreen University Journal for Studies and Scientific Research- Medical Science Series. 2006; 28(2):64- 72.
)
