Document Type : Research Paper

Author

Anbar University - College of Education for Pure Sciences

10.37652/juaps.2011.15498

Abstract

The effect of copper on some serum biochemical measurements was tested in rats
including some of the key enzymes such as Alkaline phosphatase (ALP) and Acid phosphatase (ACP)
and Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) and Lactate
Dehydrogenase (LDH) and Glucose - 6 - phosphate Dehydrogenase (G6PDH), in addition to measuring
of total protein . These biochemical measurements tested for each group of male rats , treatment and
control results showed significant changes in enzymatic activity and total protein compared to the
control group , where it was observed a significant decrease in the amount of total protein (P<0.05)
compared with a control , where the greater concentration of copper increased with low amount of total
protein . It was also observed a significant decrease (P<0.05) in the effectiveness of the enzyme
Alkaline phosphatase (ALP) concentrations in all treatment of male rats compared with control group.
The enzyme Acid phosphatase (ACP) was the cause of copper increased significantly (P<0.05) in the
effectiveness of this enzyme in all the different concentrations of copper as compared to control . In the
enzymes of the Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) , where it was
noted that increased significantly (P<0.05) in the effectiveness of the enzyme (AST) compared to
control and decrease significantly (P<0.05) the level of effectiveness of the enzyme (ALT) compared to
control . In the enzyme Lactate dehydrogenase (LDH) has been observed a significant decrease
(P<0.05) as compared to the enzyme effectively control the three transactions as a result of a copper .
In the enzyme Glucose – 6 - phosphate Dehydrogenase (G6PDH) , it was noted that increased
significantly (P<0.05) in the effectiveness of the enzyme as a result of exposure to different
concentrations of copper as compared to control .

Main Subjects

 
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