Document Type : Research Paper
Authors
1 College of Science - University of Tikrit
2 College of Education - University of Tikrit
3 College of Pharmacy - University of Tikrit
Abstract
ABSTRACT:[A,B and C] Contains formyl group were synthesized through the condensation
polymerization of [Ortho, Meta, Para] – hydroxyl benzaldehyde with formalin in basic medium. The
prepared polymers were reacted with different drugs containing amino groups [ Aldomet , Isonizide ,
Sulfamethoxazole ,Folic acid ] through condensation reaction to gives twelfth new polymers. The
structures of these polymers were characterized using [ IR, U.V] spectral data, the result obtained are
compared with their assigned structures.The prepared polymer conjugated supported drugs were
studied for controlled drug release in- vitro at following pH [7.3, 9.4, 1.2] and at constant temperature
[25C ◌ْ ] . The obtained result indicate that the polymer structure and pH media have a significant
effects on controlled drug release .
Keywords
Main Subjects
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