The relationship between insulin hormone and insulin resistance ( IR ) with Lipid profile in people with diabetes(Type I and Type II)

Almawla, Abdullah S.; Ali, Hameed H.; Farhan, Mohammed M.

doi:10.37652/juaps.2022.171599

Document Type : Research Paper

Authors

¹ University of Anbar , College of Science ,Chemistry department

² University of Anbar ,College of Science , Chemistry department

³ Al-Nahrain University , Biotechnology Research Center

https://doi.org/10.37652/juaps.2022.171599

Abstract

The study included (75 blood samples) patients of Diabetes Mellitus (DM) (30 blood sample for T1DM), (45 blood sample for T2DM). The (25 blood samples) healthy as control group and a clinical study was conducted on the samples taken. Determine the level of insulin hormone (IH) using the ELISA device and calculate the insulin resistance (IR). The level of blood glucose (F.B.S) and lipid profile were measured by spectral method. The study showed a higher significant difference between serum glucose of patients compared to the control group (P <0.05). As well as insulin resistance (IR) by (P <0.05) for the first and second types . As for the lipid profile , a significant difference was found for the concentration of (Cho, TG, LDL, VLDL) in (P <0.05) for type 2 D.M . The first type of diabetic patients was observed to have no significant difference in blood lipids.As for the correlation between insulin hormone and lipid profile and blood glucose , it was found that there was a correlation between sugar and LDL , insulin and (TG, VLDL) for patients with T1DM. For T2DM patients, there was a correlation between (IR) and level (HDL) and also between blood sugar and HDL level.

Keywords

مرض السکری هورمون الأنسولین صورة الدهون

Main Subjects

Chemistry

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Journal of University of Anbar for Pure Science

The relationship between insulin hormone and insulin resistance ( IR ) with Lipid profile in people with diabetes(Type I and Type II)

References

References

Volume 12, Issue 1
April 2018
Page 81-87

The relationship between insulin hormone and insulin resistance ( IR ) with Lipid profile in people with diabetes(Type I and Type II)

References

References

Volume 12, Issue 1April 2018Page 81-87

Volume 12, Issue 1
April 2018
Page 81-87