Document Type : Research Paper
Author
Al-Mustansiriya University - College of Science
Abstract
ABSTRACT: To investigate the effect of selenium (se) administration on gonadotropins , a total of (15)
immature female mice were injected intraperitonealy with (0.001) mg selenium once daily until
appearance of full vaginal cornification. Control mice (n=15)were injected with normal saline .Result ,
showed that appearance partial vaginal cornification was noticed 5days past (se) administration. Full
cornification was obtained on day 41of age .Serum changes in FSH,LH, and Estrogen were studied at the
age of 41 days in all animals .Result showed that a significant (p<0.05) increase in serum level of both
gonadotropins and Estrogen in( se ) treated mice ,Result of the present investigation indicate (se) ability to
stimulate gonadotropin in immature mice associated with increase level of FSH,LH, and Estrogen hormone
which delayed the age of puberty in female mice .
Main Subjects
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