Study on some predelivery immunoparameters in pregnant women in Al-Ramadi city

Naji Al-Hayani, Noor

doi:10.37652/juaps.2011.44110

Document Type : Research Paper

Author

Noor Naji Al-Hayani

AL-Anbar University- College of Medicine

10.37652/juaps.2011.44110

Abstract

Serum Protein plays major role to maintain balance of blood, so total protein may be elevated or
decreased due to some pathological & physiological changes in human body during pregnancy period. On the
other hand the serological diagnosis of antibodies level during pregnancy is usually based on the detection of IgG
and IgM antibodies as markers for diagnosis. The aim of this study was to investigate some immunoparameters
including IgM, IgG, and assay of TSP, TSA & TSG in pregnant women attending Maternity & Child Hospital in
Ramadi City, West of Iraq. Sera of 50 pregnant women were collected & quantitative assays by Single Radial
Immunodiffusion test (Mancini test) for detection of (IgM & IgG) concentration & spectrophotometric method for
Total serum protein, Total serum Albumin & Total serum Globulin reader were achieved against these serum
samples.Serum immunoglobulin (IgM & IgG) were measured in 50 pregnant women. (22) with natural delivery &
(28) Cesarean delivery pregnant women. The mean IgG level was increased in pregnant women aged under 25
years, while IgM levels were markedly increased at (25-39) years. A total mean titer for IgG & IgM were found to
be 1006.2071± 408.12282 & 48.8571±28.81962 respectively.Total serum protein reports separate values for total
protein , albumin & Globulin. Values of serum protein reflect high globulin concentration, while albumin
concentration in pregnant women recorded significant differences It is mean values for age group (15-24) & (25-
39) years are 3.4479 ± .72373 & 3.0044±.33212 respectively. There was significant differences in albumin
concentration through age group in pregnant women. Most values of serum routine liver function tests during
normal pregnancy remain below the upper normal limits in no pregnant women. When liver disease is suspected &
considered pathologic further should prompt evaluation. Furthermore, IgG concentration was predominantly
increase in their level during pregnancy in association with transported IgG through placenta to the fetus during
late pregnancy period

Keywords

Main Subjects

Biology

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Journal of University of Anbar for Pure Science

Study on some predelivery immunoparameters in pregnant women in Al-Ramadi city

References

References

Volume 5, Issue 2
August 2011
Page 25-29

Study on some predelivery immunoparameters in pregnant women in Al-Ramadi city

References

References

Volume 5, Issue 2August 2011Page 25-29

Volume 5, Issue 2
August 2011
Page 25-29