Document Type : Research Paper

Author

University of Anbar - Veterinary Medicine College

10.37652/juaps.2012.62772

Abstract

Mo(VI), and Mo(IV) complexes with two Schiff base ligands derived from salicylic acid hydrazide with 4-dimethylaminobenzaldehyde and 4-Nitrobenzaldehyde have been prepared and characterized by several techniques: infrared and electronic spectra, magnetic susceptibility, molar conductance measurements, and the metal content in complexes are estimated by gravimetric analysis. Based on this study square pyramidal structure for Mo(IV) complexes and octahedral structure for the Mo(VI) complexes are proposed. The biological activity of these are studied against two strain gram +ve bacteria (Staphalococcus auras, P.aeruginosa) and two strain gram -ve bacteria (E.coli, Enterococcus ) and yeast Candida albicans to assess their inhibiting potential. The results show the two ligands are inactive against Staphalococcus auras and they have moderate activity against the rest microbactrial organisms, the antimicrobial screening show that complex [MoO (Lb)2] exhibit the most activity against the two types of bacteria and the complex [MoO (La)2] exhibit the most activity against the yeast Candida albicans.

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Main Subjects

  1. R. N Patel, V L N Gundla & D K Patel, Synthesis, Characterization and Properties of Some ternary copper (II) complexes containing NOS donor              Schiff  base and NN donor bidentate ligands, Indian Journal of Chemistry, Vol. 47A, March 2008, pp.353-360.
  2. Shalin Kumar, Durga Nath Dhar and P N Saxena, Application of metal complexes o Schiff bases- A review, Journal o Scientific & Industrial Research, Vol. 68, March  2009, pp.1881-187.
  3. R. C. Bray., Enzymes, 12, 299 (1975).
  4. Perumaal Subramani Synthesis, Spectroscopic and Electrochemical Studies on        Molybdenum (IV),(V), and(VI) complexes with Schiff base ligand, Rasayan J. Chem. Vol. 2, No.1 (2009), 2433-246.
  5. Furniss B S, Hannaford A J,  Smith P  W G & Patchel A R, Vogel's Text of Practical Organic Chemistry, 5th edn (Pearson Education Pvt. Ltd, Singapore)  1996, p.1269.
  6. Sarika R.Yaul, Amit R. Yaul, Gaurav B. Pethe and Anand S. Aswar.  American-Eurasian Journal of sciences Research 4 (4):229-234, 2009.
  7. H. Gehrake Jr. and J. Veal, Inorg. Chem. Acta 4 (1969) 623-625.
  8. G. A. Parker, Analytical Chemistry of Molybdenum, Springer –Verlag, New York, 1983, p.29.
  9. V. A. Shelke, S. M. Jadhav S. G. Shankarwar, A. S. Munde and T. K. Chondhekar. Synthesis, Characterization, Antimicrobial and Antifungal        Studies of Some Transition and Rare Earth Complexes of N Benzyliden-2- Hyroxybenohydraide. Bull. Chem. Soc. Ethiop. (2011), 25(3), 381-391.

10. Dyer. J. R. Application of Absorption spectroscopy of organic compounds,    prentice: Hall: London, 1965  p.15.

11. Samiran Bhattachar  jee and Ramgopal Bhattacharyya. ,J. Chem. Soc. Dalton Trans., 1357 (1992).

12. Cezar, S. and K.  Angela, (2000). "Co (II), Ni (II) and Cu (II) complexes of      bidetentate Schiff base, Acta, Chim. Slov., 47, pp.179-185.

13. K. Atish Maldhure and S. Anand Aswar (2009). Electrical Conductivity  and Antimicrobial Screening of Transition Metal Complexes of     Tetradentate Unsymmetrical Ligand. World Journal of Chemistry 4 (2):207-209.

14. J.H.Pandya and M. K. Shah., Synthesis and antimicrobial propertieso Transition Metal Complexes of Noel Schiff Base Ligand Derived from 5- bromosalicyldehyde., J. Ind. Council Chem., Vol. 26, No. 2, 2009, pp. 109-112.

15. R. Rajavel, M. Senthel Vadivu and C. Anitha, synthesis physical characterization     and biological activity of some Schiff base complexes, E-Journal of Chemistry, Vol. 5, No.3,pp.620-626, July (2088).