Document Type : Research Paper

Author

University of Al-Anbar - College of medicine

Abstract

The aim of this study is determine the effect of cement dust on liver and kidney parameters that include liver enzymes (S.ALP , S.ALT ,S. AST) , total serum protein , urea and creatinine inworkers that exposing to cement dust in AL-Anbar mosaic factory . The results show that an increased in urea (workers= 46.7±0.826 , control=30.26±0.613),creatinine (workers=1.23±0.074, control=0.653±0.0601)and in S.AST activity (workers=29.3±0.809 , control=6.29±0.720) S.ALT activity(workers=24.04±1.163 , control=6.63±0.822) , while no significantly difference inS.ALP activity(workers=4±0.477, control=5.23±0.657) and serum total protein(workers=6.239±0.13 , control=6.387±0.18) when compared between theworkers and control group.

Keywords

Main Subjects

1-International Labour Organization, (1999) : Encyclopaedia of occupational health and safety. vol. 3,4th edition, pp 93.44-93.46 Geneva.
2-Smailyte, G. ;Kurtinaitis, G. and Andersen, A. (2004).Mortality and Cancer Incidence among Lithuanian cement producing worker. Occup. Environ Med. 61: 529-534.
3-Fell, A.K. ;Thomassen,T.R. ; Kristensen, P. ; Egeland, T. and Kongerud, J.(2003). Respiratory symptoms and ventilatory function in workers exposed to Portland cement . J. ocuup. Environ. Med., 45:1008-1014.
4- Gbadebo, A.M. and Bankole, O.D. (2007). Analysis of potentially toxic metals in airborne cement dust around sagamu southwestern Nigeria . J.Applied Sci., 7:35-40.
5-Rapiti, E. ;Sperati, A. andMiceli, M. (1999). End stage renal disease among ceramic workers exposed to silica. Occup. Environ. Med. 56:559-561.
6- Ding, M. ; Chen, F. ; Shi, X. ;Yucesory, B. ; Mossman, B. andVallyathan, V. (2002). Diseases caused by silica: mechanisms of injury and disease development. International Immunopharmacology.  2:173-182.
7-Smailyte G.;Kurtinaitis, G. and Andersen, A. (2004).Mortality and Cancer Incidence among Lithuanian cement producing worker. Occup. Environ Med.; 61: 529-534.
8- Meo, S. A. ; Rasheed S. ; Khan M.M. ; Shujauddin S. and Al-tuwaijri, A. (2008).Effect of cement dust exposure on phagocytic function of polymorphonuclear neutrophils in cement mill workers. International Journal of Occupational Medicine and Environmental Health.21(2):133-139.
9-Ogunbileje, J.O. ;Akinosun, O.M. ;Arinola, O.G. andAkinduti, P.A.(2010). Immunoglobulin Classes (IgG, IgA, IgM and IgE) and Liver Function tests in Nigerian Cement Factory Workers, Researcher . 4:55-58 .
10-Mohammad, A. and Abdollahi, M. (2011). A systemic review on oxidant /antioxidant imbalance in aluminium toxicity . Int.J.Pharmacol. , 7:12-21.
11-Kohen, R. and Nyska, A. (2002). Oxidation of biochemical system oxidation stress phenomena antioxidants redox reaction and methods for their quantification . Toxicol. Pathol. , 30:620-650 .
12-Adly, A.A.(2010).Oxidative stress and disease . Res. J. Immunol. , 3:129-145.
13-Merenu, I.A. (2003)The Effect of Cement Dust Exposure on Lung Function, Haematological Parameters and Liver Enzymes in Cement Factory Workers In Sokoto Metropolis. MPH dissertation, Usman Danfodio University, Sokoto, Nigeria.
14-Fell, A.K. ;Thomassen, T.R. ;Kristensen, P. ;Egeland. T. and Kongland, J.(2003) Respiratory Symptoms and Ventilatory Function in Workers Exposed to Portland Cement Dust. JOEM. 45:1008-1014.
15-Omini, O.I. ; and Akpogomeh, B.A. (2007) The effect of Limestone, Crush Rock and Asbestos /cement dust particles on the Ventilatory function parameters of chronically exposed workers in Calabar municipality and Akampka Local Goverment Areas of Calabar ,Cross River State, Nigeria. Journal of Medical laboratory Sciences. 16:1-3 .
16-Mojimoniyi, F.B.O. ;Merenu, I.A. ;Njoku, C.H. and Ibrahim, M.T.O.(2007). Regression Formulae for Predicting Hematologic and Liver Functions from Years of Exposure to Cement Factory Workers in Sokoto, Nigeria. African Journal of Biomedical Research. 10:235-240.
17-Saita, G. and Zavaglia, O. (1951). Renal function in silicotics .Med.Lav.42:41-48.
18-Goldsmith, J.R. and Goldsmith, D.F. (1993). Fiberglass or silica exposure and increased nephrites or ESRD(end-stage renal disease) . Am. J . Ind. Med. 23:873-881.
19- Steenland, K. ;Rosenman, k. ; Socie, E. and Valiante, D. (2002) Slicosis and end-stage renal disease . Scand. J. Work Environ. Health . 28:439-442.
20-Akinola, M. O. ; Okwok, N. A. andYahaya, T. (2008). The effects of cement dust on albino rats (Rattusnorvegicus) around west African Portland cement factory in Sagamu , Nigeria . Res . J. Environ Toxicol. 2:1-8 .
21-Ezejiofor, T. I. N. and Mba, I. E. K. (2003) Serum bicarbonate levels in cement factory workers a predictor for occupational lung disease . JOMIP 4:15-18.