NARJIS .A.ABDUL RAZAAG; HASSAN.A ABDUL-RATHA
Abstract
This study was conducted to investigate the role of alcoholic and watery extract of clove on the invitro Inhibition if staphylococcus aureus , which were Isolated from acute bovine ...
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This study was conducted to investigate the role of alcoholic and watery extract of clove on the invitro Inhibition if staphylococcus aureus , which were Isolated from acute bovine mastitis and the therapeutic role of these extract in mammary gland of mice which were used as animal model in experimental infection design. Inorder to study the pathogensis of these Isolates and their role on acut mastitis study included the therapeutic effect of watery extract of clove in the Mammary gland infection compared with the positive group (mice injected withs staph . aureus without treatment) .The watery extract of clove dissolved in water (300) mg /ml showed highly Inhibition effect on stuph . aureus growth in vitro so its gave ( 53.3) mm inhibition zone while the alcoholic extract which dissolved in water showed the lowest effect with (35 ) mm zone by the same concentration at (300)mg/ml . study inclued also the therapeutic effect of daily orally treatment dose 100mg /ml of watery extract of clove in the patgogensis of staph.aureus in these treatment period continous (30) day after 48hr of injection 125cfu/ml in mice in addition to use positive control group (mice injected with staph . aureus with out any treat ment) , clinical signs were shown side effect of clove extract after 15 day of treatment . histological study showed the role of clove extract it’s the same as histopathologcal changes in compared with the negative control and the mammary gland of these animal showed negative growth for staph.aureus .
